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It terms of where to inject Semaglutide, it must be injected subcutaneously (into the fat layer)

Keep the vial in its original box or wrap it in aluminum foil

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Key sources of advice include: Your dispensing pharmacist community and hospital pharmacists are trained in medicines storage and can advise on what to do if storage conditions have been compromised Your GP or prescribing clinician particularly important if you are receiving retatrutide through a clinical trial or named-patient supply The clinical trial coordinator or sponsor if you are a trial participant, the trial team should be your first point of contact for any medicine-related concerns, including storage queries and cold-chain breaches NHS 111 available 24 hours a day for urgent medicines advice when your usual healthcare team is unavailable The Specialist Pharmacy Service (SPS) provides authoritative UK guidance on medicines requiring refrigeration, maintaining the cold chain, and handling storage breaches

When to consider adjusting your GLP-1 dose Sometimes constipation is severe enough that it affects quality of life despite implementing all the strategies above